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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLG4 All Species: 21.82
Human Site: Y432 Identified Species: 60
UniProt: P78352 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78352 NP_001356.1 724 80495 Y432 S N P K R G F Y I R A L F D Y
Chimpanzee Pan troglodytes XP_523833 721 80070 Y429 S N P K R G F Y I R A L F D Y
Rhesus Macaque Macaca mulatta XP_001098707 880 97846 Y585 T S Q K R S L Y V R A L F D Y
Dog Lupus familis XP_546580 760 84228 Y474 S N P K R G F Y I R A L F D Y
Cat Felis silvestris
Mouse Mus musculus Q62108 724 80454 Y432 S N P K R G F Y I R A L F D Y
Rat Rattus norvegicus P31016 724 80447 Y432 S N P K R G F Y I R A L F D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ00 468 52501 G191 A G L K F Q T G D V I Q I I N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6R005 801 89122 F511 R S G K R S F F I R A L F D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P31007 970 106654 G678 D N E D E Q I G I V P S K R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 62.5 89.6 N.A. 99.5 99.8 N.A. N.A. 21.8 N.A. 71.2 N.A. 44.5 N.A. N.A. N.A.
Protein Similarity: 100 99.1 72.7 91.5 N.A. 99.8 99.8 N.A. N.A. 38.2 N.A. 79.4 N.A. 58 N.A. N.A. N.A.
P-Site Identity: 100 100 60 100 N.A. 100 100 N.A. N.A. 6.6 N.A. 66.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. N.A. 13.3 N.A. 80 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 0 0 0 78 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 12 0 0 0 0 12 0 0 0 0 78 0 % D
% Glu: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 12 0 67 12 0 0 0 0 78 0 0 % F
% Gly: 0 12 12 0 0 56 0 23 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 78 0 12 0 12 12 0 % I
% Lys: 0 0 0 89 0 0 0 0 0 0 0 0 12 0 0 % K
% Leu: 0 0 12 0 0 0 12 0 0 0 0 78 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 0 56 0 0 0 0 0 0 0 12 0 0 0 0 % P
% Gln: 0 0 12 0 0 23 0 0 0 0 0 12 0 0 0 % Q
% Arg: 12 0 0 0 78 0 0 0 0 78 0 0 0 12 12 % R
% Ser: 56 23 0 0 0 23 0 0 0 0 0 12 0 0 0 % S
% Thr: 12 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 12 23 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 78 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _